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Dr Anita Oberbauer of University of California Davis is currently conducting the research project into finding the DNA marker for Addison's disease.
This disease can cause devastation and heartbreak ,Eddie's story is not unique. Many vet's are not aware of it's prevelance in Bearded Collies and Standard Poodle's even now. Many stories I have heard as the result of printing Eddie's story is that diagnoses is often made by luck rather than by good management. Once it has been diagnosed,treatment is expensive and lifelong, or pretty final as in Eddie's case.
The scientists in America are on the verge of finding the DNA marker for Addison's .What the research team require however is more genetic material.
This is were anyone with a Bearded Collie or Standard Poodle(Leonbergers,Portuguese Water Dogs & Westie's are also required) with known ancestry can help.
The DNA test is taken in the form of 3 cheek swabs.Undertaken by you the owner in the privacy of your own home.Full instructions are given and a very short questionnaire has to be completed. An addressed envelope is provided also for the return of the samples to the USA.
All it takes is a little of your time and approx one pound in postage. Both healthy and Addisons dogs are required for the project.
Pedigrees are coded so that researchers do not know the names of affected dogs or those that have produced the disease , so it is confidential.
Please only request a swab kit if you will use it.
If you have a Standard Poodle and wish to help please contact me Michelle Hargreaves by e-mail : ollieddie@wendymut.fsnet.co.uk
If you wish to help and have a Bearded Collie please contact Jo Tucker by e-mail:jo@cimda.fsnet.co.uk
Alternatively you can also visit The researches website to look at the work being undertaken or request a kit directly from them at:
http://cgap.ucdavis.eduThe Latest Update From Dr Oberbauer In The US:
Bearded Collies
9.4% of the submitted BCs were addisonian.Hypoadrenocorticism is highly heritable with a heritability estimate of 0.76. Both sexes are affected equally . The statistical evidence does not fully support a single autosomal recessive major locus but the evidence is quite strong. Standard Poodles
8.6% of the submitted Standard Poodles were Addisonian. Similar to the condition in Bearded Collies, hypoadrenocorticism is highly heritable with a heritability estimate of 0.75. There is no coat color nor sex association with the disorder. There is strong statistical evidence that the disorder is regulated by a single autosomal recessive locus but the definitive affected to affected breeding hasn't been reported.
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